WebOct 31, 2011 · Spironolactone is commonly used in decompensated liver cirrhosis to either prevent or treat ascites formation. Most patients ,due to WebFor spironolactone Oedema, Ascites in cirrhosis of the liver for spironolactone By mouth. Adult 100–400 mg daily, adjusted according to response. Malignant ascites for spironolactone By mouth. Adult Initially 100–200 mg daily, then increased if necessary to 400 mg daily, maintenance dose adjusted according to response.
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WebSpironolactone 100 mg per day in combination with oral furosemide 40 mg per day is suggested for initial treatment of ascites. Spironolactone and furosemide are titrated gradually based upon response using a ratio of 100 mg spironolactone to 40 mg furosemide. Refer to UpToDate topic on initial therapy of ascites in adults with cirrhosis ... WebOct 14, 2024 · Spironolactone is an aldosterone receptor antagonist and potassium-sparing diuretic widely used in the therapy of edema, particularly in patients with cirrhosis in which hyperaldosteronism appears to play a … kpsc fda hall ticket download
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WebIntroduction: The present study was conducted to compare the efficacy and side effects of Spironolactone and Eplerenone in management of ascites due to liver cirrhosis. Materials and methods: 105 patients of ascites with liver cirrhosis were randomized into three groups of 35 patients each. Group I was given Spironolactone 100 mg, group II was given … WebMar 6, 2024 · Detailed Spironolactone dosage information for adults. Includes dosages for Hypertension, Edema, Congestive Heart Failure and more; plus renal, liver and dialysis adjustments. ... Treatment of edematous conditions in patients with liver cirrhosis accompanied by edema and/or ascites. WebJul 27, 2024 · Spironolactone, an aldosterone antagonist, is the most commonly used diuretic for patients with cirrhosis and ascites. Spironolactone competitively binds the receptors at the aldosterone-dependent sodium-potassium exchange site in the distal convoluted renal tubule, resulting in a potassium-sparing diuretic effect. many hands make light work images